If you spend more than 4 hours in flight, you may experience jet lag. Jet lag is the condition whereby your inner body clock is out of whack with the clock at your actual destination.
Your body is basically in limbo and needs time to adjust. You can facilitate the adjustment process by trying to acclimate to the schedule at your new location as quickly as possible. For instance, if you feel like you're ready to go to bed and it's only 2pm, do your best to stay awake until nightfall. Try to wake up when it's daylight.
If you are going "back in time" (that is, flying from east to west), try to do something active once you land. Go for a walk around your new locale.
If you are jumping "forward in time" (going from west to east), engage in calming, quiet activities that evening to try to get your body to rest. Don't sleep in, even if you're tempted to.
Above all, give yourself a few days for your body to adjust to your new time zone. If you can, don't plan any major appointments or meetings the day after you land.

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